5 Common Side Effects Of PE Medicines In Men

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In this article, we’ll discuss some common side effects of PE medicines in men.


Premature ejaculation (PE) is referred to as the condition when a man achieves orgasm much sooner than normal men would. Typically, ejaculating within under a minute of penetration is considered as an A-grade PE symptom. This leaves neither the partner satisfied and also leaves the man responsible in a state of embarrassment. Are you wondering why does PE happen? There is no sure-shot reason that has been figured, but there are a few factors that have proven to be the reason behind PE in men.

  • Performance anxiety: Regarding whether the man can do well in bed and satisfy his partner or not
  • Hereditary issues: If your parents and grandparents suffered from ED, there is a high chance that even you will
  • Relationship issues: When there is friction in a relationship, lower levels of compatibility, and guilt due to some problems and fights can lead to PE
  • Poor lifestyle: Leading a poor lifestyle that involves ample of stress and no forms of mental or physical exercise can give rise to PE
  • Unhealthy consumption habits: Consuming alcohol in copious amounts and smoking too much tobacco will inevitably lead to further PE issues

What Is The Solution?

PE victims usually need to consume SSRIs (Selective Serotonin Reuptake Inhibitors) as few of the side effects of these medicines are delayed ejaculation. Consider consuming medicines such as Sertraline (Zoloft), Fluoxetine (Sarafem or Prozac), Paroxetine (Paxil), Escitalopram (Lexapro).

Side Effects Of PE Medicines

However, just like 99 percent of the medicines available within the pharmaceutical industry, even PE medication comes with a number of side effects. If you are already consuming existing medication that has visible side effects then it would be wise to know the side effects of PE medication to avoid similar and more intense side effects. We have curated a list of side effects that are common with PE medication.

1. Penile Sensitivity

This problem is evident only if topical anesthetic creams are used to treat PE. These creams basically function by numbing the penile structure and making it less sensitive to touch and to the brushing inside the vagina during intercourse. If penile sensitivity is reduced then a man can naturally hold on to his orgasm and increase ejaculation time by a considerable duration.

The side effect here is that too much of cream or frequent usage of such creams can lead to making the penis highly insensitive and reduce the pleasurable moments during sexual activity.

Even worse, during penetration, the cream enters the female’s vagina and even she can begin to have a less pleasurable sexual experience due to lowered sensitivity. Make sure the cream is washed away after sex to avoid losing your erection-maintaining ability or becoming a victim of vaginal numbness (if you are a female and your partner is using such creams).

2. Nausea And Drowsiness

SSRIs are known to treat depression issues in the CNS (Central Nervous System). This is done by causing a spike in serotonin levels present in the brain. One must know that serotonin is a neurotransmitter that is responsible for transmitting signals between neurons in the body. What SSRIs do is that they restrict the reabsorption of serotonin back into the brain.

Consuming too much of SSRIs can easily lead to nausea and dizziness, along with a frequent occurrence of headaches. The period that these side effects last depend on the overall health of your body. In most cases, the immune system repairs the problems and these side effects would cease to exist within a few weeks of stopping consumption.

3. Sleep Problems

SSRIs are also responsible for causing a dry mouth and sleep problems. This happens due to nausea and dizziness that alters several hormonal levels within the human body. Research suggests that occasional headaches, drowsiness, and a low desire to have sex can also occur due to common mood swings. Thus one cannot always blame the medication that they are consuming.

Most often these side effects arise when the consumption is SSRI medication is abruptly stopped. The body takes time to forget the usual addition of SSRIs that it has been receiving. Rather than randomly stopping your SSRI prescription, you must gradually shift to lower doses and eventually stop completely.

4. Flushing Of The Skin

This side effect is common when the type of medicines being consumed for PE comes under the category of PDE-5 (phosphodiesterase type 5) inhibitors. Medicines such as sildenafil citrate 100mg, vardenafil 20mg (generic Levitra 20mg, Staxyn), and tadalafil 20mg (Cialis, Adcirca) are PDE-5 inhibitors that contribute to treating impotence problems such as erectile dysfunction (ED). Expect to face mild to moderate gastrointestinal problems, reddening of the skin, and headaches to occur.

5. Hidden Deterioration Within Your Body That Worsens Over Time

This is a grave situation of consuming PE medicines and can only arise if an individual does not purchase the medicines from an authorized and reputed source. Over the counter (OTC) may do just fine if they are purchased at a pharmacy. But consuming PE medicines from websites?

This is definitely one of the most dangerous routes one can take to cure the PE problem. The FDA has run some tests by ordering PE and ED medicines from online pharmacies. Guess what? Over 3/4th of these medicines were counterfeit versions, had an inaccurate ingredient composition, used industrial chemicals, and were not tested prior to sale.

Online pharmacies that are not regulated by health organizations have the freedom to manufacture and sell medicines without any quality checks. This is why they focus on mass production and mass sales rather than prioritizing the health of their customers.

Many times when such medicines were tested for potency, the kind of ingredients found in the product would come as a shock to you. Blue ink, industrial paint, and rat poison were few of the ingredients used to make the consumer feel like they are on some heavy medication.

Side Effects Of PE Medicines: Conclusion

Premature ejaculation medicines are safe for consumption only as long as they are purchased from a regulated and authorized source. Considering you already have a less interesting sex life due to your poor sexual health, these fake medicines would only worsen your condition and add to the list of deficiencies you have in bed. To stay safe and let the side effects of PE medication stay at par, you must consume them responsibly and for extra security, consult your doctor.


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