MIFEPRISTONE

Everything you need to know to buy Mifepristone online & How to use it?

Consume Misoprostol containing 800 mcg (200 mcg each of 4 pills) after the Mifepristone pill. Insert Misoprostol pills under the tongue. They shouldn’t be chewed, crushed, broken, and swallowed. But after 30 minutes it can be consumed without water and that too after it completely melts under the tongue. This medication is a prostaglandin analog which leads to the contractions of the womb. When the uterus contracts, it tries to reveal out or push out the pregnancy remaining. During this, women experience heavy bleeding and cramps for a couple of hours or days.

What are the dosages and administrations of Mifepristone?

Prescription of Mifepristone to women is for the medical termination of intrauterine pregnancy. The intake of pills is possible up to 9 weeks gestation based on the first day of amenorrhea or last menstrual period. For this treatment, the doctor considers pregnancy from the first day of amenorrhea in a presumed 28-day cycle, with ovulation occurring at mid-cycle.

It is essential to determine the duration of pregnancy from menstrual history and by clinical examination. If the period of pregnancy is uncertain, ultra-sonogram (USG) scan is a must. In case of suspicion of ectopic pregnancy, usage of USG eradicates pregnancy.

Remove any intrauterine device (IUD) before using the kit. Pregnancy termination by surgery is the case of Mifepristone failure to cause intrauterine pregnancy termination.

A gynecologist administers Mifepristone after gestational age assessment of the fetus. In case of negative results, the advice might be to diagnose ectopic pregnancies. The gynecologist should also be able to perform the surgical intervention in cases of severe bleeding or incomplete abortion.

Consume Mifepristone 200mg initially and after three days follow the oral intake of Misoprostol 800mcg (4 pills of 200mcg). A trained medical professional may administer Misoprostol, or it can also be self-administered by the woman. If the abortion doesn’t occur after administration of Misoprostol, a second dose with 400mcg is likely to administer orally.

Usually, the patient using Mifepristone should return for a follow-up visit after 7-14 days of administration. The follow-up is to confirm that a complete pregnancy termination has occurred with the help of a clinical examination or USG scan. There is a risk of fetal malformation if the patients have an ongoing pregnancy at this follow-up visit. In such a case, surgical termination might be advisable.

For patients using Mifepristone tablets

• This medicine is prescribed only by your doctor. The entire treatment only requires three visits to your doctor.
• At the first visit, a prescription of one mifepristone tablet is likely to happen. Two days later, on the second visit, you will be prescribed another four pills of Misoprostol. During the third visit after two weeks, your doctor will confirm the status of your pregnancy. The process may include an ultrasound exam (sonogram) for confirmation of abortion.
• Misoprostol will cause you to bleed and have cramps for about 2 to 4 weeks. Call your doctor if you have little or no vaginal bleeding after consumption of the medicine.
• It is sometimes necessary to have a surgical abortion to end the pregnancy ultimately. You might need surgery if there is any tissue left in the uterus after treatment with mifepristone.
• Tell your doctor if you are using an intrauterine device (IUD). Removal of IUD will take place before using the medicine.

What are the contraindications?

Administration of Mifepristone contraindicated in patients who have:

• history of Mifepristone and Misoprostol allergy
• suspected or confirmed an ectopic pregnancy
• migraine issues
• IUD in place
• chronic adrenal failure
• bleeding disorders
• anticoagulant, corticosteroid therapies
• inherited porphyria
• severe uncontrolled asthma

Above mentioned issues are not a complete list of contraindications, but in case you face any other, talk to your doctor and find suggestions on the other problems.

Mifepristone might turn out to be an issue if a patient has no adequate access to medical facilities. In turn, she needs emergency treatment in case of an incomplete abortion, blood transfusions, and emergency resuscitation. To know more about contradictions please visit the following page https://www.webmd.com/drugs/2/drug-20222-1449/mifepristone-oral/mifepristone-300-mg-oral/details/list-contraindications.

What are the warnings and precautions?

Mifepristone is not a recommendation to patients with renal failure, hepatic failure, and malnutrition. The administration of Mifepristone must be under the supervision of a certified gynecologist.

Currently, there are no data on the safety and effectiveness of Mifepristone in women with chronic diseases such as heart disease, hypertension, liver dysfunction, respiratory or kidney disease, insulin-dependent diabetes, severe anemia, or heavy smoking. Women above 35 years of age who smoke need treatment with great caution.

Studies in animals or humans have demonstrated fetal abnormalities, and there is positive evidence of human fetal risk. The survey confirms with a base on adverse reaction data from investigational or marketing experience. Also, there are risks involved in the use of the drug in pregnant women that outweigh potential benefits.

Patients should be well aware of the Mifepristone administration and its effects. They must understand the necessity of the treatment and the importance of doctor visits. Another pregnancy may occur following the termination of pregnancy. So, contraception must be initiated soon after using the Mifepristone before the woman resumes sexual intercourse. Please note that clinical examination is imperative to confirm the complete pregnancy termination after the treatment.

In some women, a decrease in hemoglobin concentration, hematocrit, and red blood cell count may occur for those who bleed heavily.

Comments on using Misoprostol

• Medication for cramps or gastrointestinal symptoms may be needed during the period immediately following the administration of Misoprostol.
• The effectiveness of the regimen may be lower in few cases. The cases might occur due to Mifepristone administration is less than 24 hours or more than 48 hours.
• Most women will come out of the pregnancy within 2 to 24 hours of taking Misoprostol. An appropriate location for the patient is essential in the administration of Misoprostol, taking into account that the initiation of abortion could begin within 2 hours of administration.
• For purposes of this treatment (pregnancy termination), doctors generally consider pregnancy dates from the first day of the last menstrual period.
• Doctors determine the duration of pregnancy from menstrual history and clinical examination.
• Assessment of the fertility is by ultrasonography scan if the length of pregnancy is uncertain or if ectopic pregnancy is suspected.

What are the drug interactions?

No specific drug or food interactions with Mifepristone aren’t studied. However, there is a possibility that certain drugs and substances such as ketoconazole, itraconazole, erythromycin, and grapefruit could inhibit the metabolism of Mifepristone. Also, dexamethasone, rifampicin, and certain anticonvulsants may induce Mifepristone metabolism.

Misoprostol, on the other hand, has not been found to interfere with the effects of aspirin. It does not exert a clinical impact on the absorption and antiplatelet effects of aspirin. Drug interaction studies between Misoprostol and several NSAIDs had no clinical implications for ibuprofen, diclofenac, piroxicam, aspirin, naproxen, or indomethacin.

Antacids continuing magnesium should be avoided during treatment with Mifepristone, as this may worsen diarrhea caused by Misoprostol.

There are restrictions on the usage of certain medicines to be used together. But, in other cases, two different drugs may be used together even if an interaction might occur. In either of the cases, your doctor may want to change the dose, or other precautions may be necessary.

You must report to your doctor the intake of all the medicines that you have been using. Below is the mentioned list of medications that you might be consuming for one or the other reasons. However, the following interactions are just selected based on their potential significance and are not necessarily all-inclusive. There might be a few different combos’ of intake you might follow as prescribed by your doctor.

Using Mifepristone with multiple medicines is usually not recommended, but may be required in some cases. Your doctor may change the dose or suggest a way of your dosage intake with a combination of medicines. Please consult your doctor before using the medicine.

What are the side effects?

Mifepristone may induce vaginal bleeding and uterine cramping during the process of abortion. Many women who receive Mifepristone, Misoprostol, may report a side effect. Others say more than one such reaction. More than 90 percent of patients report side effects on the third day of the treatment procedure.

Women typically experience pain in the abdomen due to uterine cramping. Others commonly report adverse effects that include nausea, vomiting, and diarrhea. Rarely, some women may experience pelvic pain, headache, and dizziness. After the third day of treatment, the incidence of side effects declined progressively, meaning that by the 14th day, no side effects might take place except for bleeding and spotting.

What is the case of overdose?

Intolerance studies report no severe side effects where the administration of Mifepristone in a single dose is higher than threefold that advised for pregnancy termination. In case of accidental massive ingestion, one may experience signs of adrenal failure. In the case of acute intoxication, one may require special treatment, including dexamethasone administration.

The toxic dose of Misoprostol in humans is not determined yet. However, a total daily dose of 1600 mcg has been tolerated well, with only symptoms of gastrointestinal discomfort. Signs of an overdose include tremor, sedation, convulsions, breathlessness, abdominal pain, diarrhea, fever, hypotension, and bradycardia. In cases of overdose, seek medical attention right away.

Where should I store Mifepristone?

Mifepristone needs to be stored at room temperature, preferably away from moisture, heat, and sunlight. Keep the container tightly closed with the cap provided. Always maintain a distance away from children and pets. Read all patient information, medication guide, and instructions provided to you. Follow the guidelines as mentioned on the pack if you have any questions related to storing Mifepristone.

Buy Mifepristone Online: FAQs

Now that you are done reading all the necessary information; here are some of the most frequently asked questions that patients have on how to buy Mifepristone online & use it to get the best results.

Will I vomit after taking the Mifepristone pill?

Some women do feel nauseating after taking the pill. Check with the doctor if you think nauseated or vomit; you may need an antiemetic drug to stop vomiting.

What to do if I accidentally swallowed Misoprostol pills?

Misoprostol pills are safe and usually effective if swallowed. However, there may be some gastrointestinal effects when the intake of tablets directly enters the stomach.

Does Mifepristone affect my fertility?

Buy Mifepristone online because it does not have any long-term impact on your health or fertility. Most women will ovulate within a few weeks and will resume their menstruation within four weeks after pregnancy termination. So, a woman can become pregnant within weeks of using Mifepristone.

When can I resume sexual intercourse after the treatment?

Generally, women are advised not to participate in sexual intercourse for at least one week after the treatment with Mifepristone.

Will I have any psychological disturbances after treatment?

It is unlikely so. Early medical termination of pregnancy is often associated with an increase in psychological disturbances such as depression and anxiety. The risk of mental health problems is less with Mifepristone treatment.

Is it safe to Buy Mifepristone Online online?

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